GRIK3 anticorps (N-Term)

N° du produit ABIN6990822

Détail du produit anti-GRIK3 anticorps

Antigène: GRIK3 (Glutamate Receptor, Ionotropic, Kainate 3 (GRIK3))

Épitope: AA 30-80, N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIK3 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Grik3 Antibody is affinity chromatography purified via peptide column.

Immunogène: Grik3 antibody was raised against a 13 amino acid synthetic peptide near the amino terminus of the human Grik3. The immunogen is located within amino acids 30 - 80 of Grik3.

Isotype: IgG

Information d'application

Indications d'application: Grik3 antibody can be used for detection of Grik3 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Grik3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: Grik3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur GRIK3

Antigène: GRIK3 (Glutamate Receptor, Ionotropic, Kainate 3 (GRIK3))

Autre désignation: Grik3 (GRIK3 Produits)

Synonymes: anticorps GRIK3, anticorps eaa5, anticorps glr7, anticorps glur7, anticorps 9630027E11, anticorps GluK3, anticorps GluR7-3, anticorps Glur-7, anticorps Glur7, anticorps GluR7, anticorps gluR-7, anticorps EAA5, anticorps GLR7, anticorps GLUR7, anticorps GluR7a, anticorps glutamate ionotropic receptor kainate type subunit 3, anticorps glutamate receptor, ionotropic, kainate 3 L homeolog, anticorps glutamate receptor, ionotropic, kainate 3, anticorps GRIK3, anticorps grik3.L, anticorps Grik3

Sujet: Grik3 Antibody: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik3, also known as glutamate receptor 7, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Grik3 is highly homologous to the related ionotrophic glutamate receptors Grik2 and Grik1. Grik3 has recently been shown to be an essential subunit of presynaptic kainate autoreceptors at hippocampal mossy fiber synapses as grik3-null mice show significantly reduced short- and long-term synaptic potentiation. Other reports have suggested that different polymorphisms in the Grik3 protein may be associated with neurological defects such as recurrent major depressive disorder and schizophrenia. This Grik3 antibody does not cross-react with Grik2.

ID gène: 2899

UniProt: Q13003

Pathways: Synaptic Membrane