KLRA1 anticorps (AA 140-190)

N° du produit ABIN6991052

Détail du produit anti-KLRA1 anticorps

Antigène: KLRA1 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 1 (KLRA1))

Épitope: AA 140-190

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLRA1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: At least three isoforms of KLRA1 are known to exist, this antibody recognizes only the long isoform.

Purification: KLRA1 Antibody is affinity chromatography purified via peptide column.

Immunogène: KLRA1 antibody was raised against a 13 amino acid synthetic peptide near the center of human KLRA1. The immunogen is located within amino acids 140 - 190 of KLRA1.

Isotype: IgG

Information d'application

Indications d'application: KLRA1 antibody can be used for detection of KLRA1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 4 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: KLRA1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: KLRA1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur KLRA1

Antigène: KLRA1 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 1 (KLRA1))

Autre désignation: KLRA1 (KLRA1 Produits)

Synonymes: anticorps Klra2, anticorps Ly49i8, anticorps A1, anticorps Klra22, anticorps Ly49a, anticorps Ly49o<129>, anticorps Ly49v, anticorps LY49, anticorps KLRA1, anticorps Ly49, anticorps killer cell lectin-like receptor, subfamily A, member 1, anticorps killer cell lectin-like receptor subfamily A, member 1, anticorps Klra1, anticorps KLRA1, anticorps LY49

Sujet: KLRA1 Antibody: KLRA1 (also known as Ly49L) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA1 is thought to be an activating receptor, inducing DAP12 phosphorylation in response to antibody-mediated cross-linking of KLRA1 on NK cells.

ID gène: 10748