KLRA1 anticorps (Center)

N° du produit ABIN783572

Détail du produit anti-KLRA1 anticorps

Antigène: KLRA1 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 1 (KLRA1))

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLRA1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 13 amino acid peptide near the center of human KLRA1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur KLRA1

Antigène: KLRA1 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 1 (KLRA1))

Autre désignation: KLRA1 (KLRA1 Produits)

Synonymes: anticorps Klra2, anticorps Ly49i8, anticorps A1, anticorps Klra22, anticorps Ly49a, anticorps Ly49o<129>, anticorps Ly49v, anticorps LY49, anticorps KLRA1, anticorps Ly49, anticorps killer cell lectin-like receptor, subfamily A, member 1, anticorps killer cell lectin-like receptor subfamily A, member 1, anticorps Klra1, anticorps KLRA1, anticorps LY49

Sujet: KLRA1 (also known as Ly49L) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA1 is thought to be an activating receptor, inducing DAP12 phosphorylation in response to antibody-mediated cross-linking of KLRA1 on NK cells. At least three isoforms of KLRA1 are known to exist, this antibody recognizes only the long isoform.Synonyms: KLRA-1, Killer cell lectin-like receptor subfamily A, LY49A, LY49L, Lymphocyte antigen 49a, T lymphocyte antigen A1, member 1

ID gène: 10090

UniProt: P20937