LRFN1 anticorps (C-Term)

N° du produit ABIN6991075

Détail du produit anti-LRFN1 anticorps

Antigène: LRFN1 (Leucine Rich Repeat and Fibronectin Type III Domain Containing 1 (LRFN1))

Épitope: AA 700-750, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRFN1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificité: This antibody is predicted to not cross-react with other members of the LRFN family.

Purification: LRFN1 Antibody is affinity chromatography purified via peptide column.

Immunogène: LRFN1 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human LRFN1. The immunogen is located within amino acids 700 - 750 of LRFN1.

Isotype: IgG

Information d'application

Indications d'application: LRFN1 antibody can be used for detection of LRFN1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: LRFN1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: LRFN1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur LRFN1

Antigène: LRFN1 (Leucine Rich Repeat and Fibronectin Type III Domain Containing 1 (LRFN1))

Autre désignation: LRFN1 (LRFN1 Produits)

Synonymes: anticorps SALM2, anticorps BC004018, anticorps Semo1, anticorps leucine rich repeat and fibronectin type III domain containing 1, anticorps LRFN1, anticorps Lrfn1

Sujet: LRFN1 Antibody: LRFN1 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system. At least two isoforms of LRFN1 are known to exist.

ID gène: 57622

UniProt: Q9P244

Pathways: Synaptic Membrane