ZBED1 anticorps (AA 180-230)

N° du produit ABIN6991091

Détail du produit anti-ZBED1 anticorps

Antigène: ZBED1 (Zinc Finger, BED-Type Containing 1 (ZBED1))

Épitope: AA 180-230

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZBED1 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: This antibody is predicted to have no cross-reactivity to ZBED2 or ZBED3.

Purification: ZBED1 Antibody is affinity chromatography purified via peptide column.

Immunogène: ZBED1 antibody was raised against a 15 amino acid synthetic peptide from near the center of human ZBED1. The immunogen is located within amino acids 180 - 230 of ZBED1.

Isotype: IgG

Information d'application

Indications d'application: ZBED1 antibody can be used for detection of ZBED1 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: ZBED1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: ZBED1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur ZBED1

Antigène: ZBED1 (Zinc Finger, BED-Type Containing 1 (ZBED1))

Autre désignation: ZBED1 (ZBED1 Produits)

Synonymes: anticorps ZBED1, anticorps ZBED1P, anticorps ALTE, anticorps DREF, anticorps TRAMP, anticorps hDREF, anticorps zinc finger BED-type containing 1, anticorps zinc finger, BED-type containing 1, anticorps ZBED1, anticorps zbed1

Sujet: ZBED1 Antibody: ZBED1, also known as DREF, is the human homolog of the Drosophila protein DREF, a transcriptional regulatory factor required for expression of genes involved in DNA replication and cell proliferation. RNA interference (RNAi) experiments targeting ZBED1 RNA resulted in the inhibition of S phase entry and reduction of histone H1 mRNA in HeLa cells, suggesting that ZBED1 also plays a role in cell proliferation in human cells. At least 22 ribosomal proteins (RPs) possess ZBED1 binding sites in their promoters, anti-ZBED1 RNAi also resulted in decreased RP gene expression. Immunoprecipitation analyses have shown that ZBED1 self-associates in vivo via a carboxyl-terminal hATC domain, and this self-association is required for nuclear localization and DNA binding.

ID gène: 9189

UniProt: O96006