IRF2BP2 anticorps (N-Term)

N° du produit ABIN6991273

Détail du produit anti-IRF2BP2 anticorps

Antigène: IRF2BP2 (Interferon Regulatory Factor 2 Binding Protein 2 (IRF2BP2))

Épitope: AA 150-200, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF2BP2 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: At least two isoforms of IRF2BP2 are known to exist, this antibody will detect both.

Purification: IRF2BP2 Antibody is affinity chromatography purified via peptide column.

Immunogène: IRF2BP2 antibody was raised against an 17 amino acid synthetic peptide near the amino terminus of human IRF2BP2. The immunogen is located within amino acids 150 - 200 of IRF2BP2.

Isotype: IgG

Information d'application

Indications d'application: IRF2BP2 antibody can be used for detection of IRF2BP2 by immunohistochemistry at 5 μ,g/mL.

Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: IRF2BP2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: IRF2BP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur IRF2BP2

Antigène: IRF2BP2 (Interferon Regulatory Factor 2 Binding Protein 2 (IRF2BP2))

Autre désignation: IRF2BP2 (IRF2BP2 Produits)

Synonymes: anticorps E130305N23Rik, anticorps IRF-2BP2, anticorps 5n852, anticorps irf2bp2-A, anticorps IRF2BP2, anticorps fj35c12, anticorps irf2bp2b, anticorps wu:fj35c12, anticorps zgc:56251, anticorps IRF-2-binding protein 2-B, anticorps IRF-2BP2-B, anticorps irf2bp2, anticorps irf2bp2a, anticorps wu:fa12b04, anticorps wu:fb73g01, anticorps zgc:63864, anticorps interferon regulatory factor 2 binding protein 2, anticorps interferon regulatory factor 2 binding protein 2 L homeolog, anticorps interferon regulatory factor 2 binding protein 2a, anticorps interferon regulatory factor 2 binding protein 2b, anticorps Irf2bp2, anticorps IRF2BP2, anticorps irf2bp2.L, anticorps irf2bp2a, anticorps irf2bp2b

Sujet: IRF2BP2 Antibody: IRF2BP2, like the related protein IRF2BP1, is a co-repressor that interacts specifically with the C-terminal repression domain of Interferon Regulatory Factor 2 (IRF2). IRF2BP2 is a direct target gene of p53 and is involved in cell survival during the p53 stress response, able to impede the p53-mediated transactivation of p21 and Bax. IRF2BP2 is also a co-factor of VGLL4 and is required to induce the expression of vascular endothelial growth factor A (VEGF-A) in muscle. It is normally found in the nucleus of skeletal muscle and cardiac cells, but can be found in the cytoplasm during skeletal muscle differentiation.

ID gène: 359948

NCBI Accession: NP_892017

UniProt: Q7Z5L9