ATP11A anticorps (N-Term)

N° du produit ABIN6991379

Détail du produit anti-ATP11A anticorps

Antigène: ATP11A (ATPase, Class VI, Type 11A (ATP11A))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP11A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Purification: ATP11A Antibody is affinity chromatography purified via peptide column.

Immunogène: ATP11A antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human ATP11A. The immunogen is located within the first 50 amino acids of ATP11A.

Isotype: IgG

Information d'application

Indications d'application: ATP11A antibody can be used for detection of ATP11A by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: ATP11A Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: ATP11A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur ATP11A

Antigène: ATP11A (ATPase, Class VI, Type 11A (ATP11A))

Autre désignation: ATP11A (ATP11A Produits)

Synonymes: anticorps ATPIH, anticorps ATPIS, anticorps 4930558F19Rik, anticorps AU040868, anticorps Atpc1h, anticorps Ih, anticorps Ua20, anticorps si:dkey-251i8.1, anticorps ATPase phospholipid transporting 11A, anticorps ATPase, class VI, type 11A, anticorps ATP11A, anticorps Atp11a, anticorps atp11a

Sujet: ATP11A Antibody: ATP11A is a widely expressed integral membrane ATPase. ATP11A is probably phosphorylated in its intermediate state and likely drives the transport of ions such as calcium or other molecules across membranes. While the exact molecule ATP11A transports is unknown, increased expression of ATP11A mRNA has been observed in murine leukemia cells made resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs). Furthermore, overexpression of ATP11A provided protection against the FTI SCH66336 while knockdown of ATP11A via siRNA made cells more sensitive to this drug. Other reports suggest that elevated levels of ATP11A mRNA may also be a predictive marker of metastasis in colorectal cancer patients.

ID gène: 23250

NCBI Accession: NP_115565

UniProt: P98196