ATP11A anticorps (N-Term)

N° du produit ABIN783659

Détail du produit anti-ATP11A anticorps

Antigène: ATP11A (ATPase, Class VI, Type 11A (ATP11A))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP11A est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 19 amino acid peptide near the amino terminus of human ATP11A

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur ATP11A

Antigène: ATP11A (ATPase, Class VI, Type 11A (ATP11A))

Autre désignation: ATP11A (ATP11A Produits)

Synonymes: anticorps ATPIH, anticorps ATPIS, anticorps 4930558F19Rik, anticorps AU040868, anticorps Atpc1h, anticorps Ih, anticorps Ua20, anticorps si:dkey-251i8.1, anticorps ATPase phospholipid transporting 11A, anticorps ATPase, class VI, type 11A, anticorps ATP11A, anticorps Atp11a, anticorps atp11a

Sujet: ATP11A is a widely expressed integral membrane ATPase. ATP11A is probably phosphorylated in its intermediate state and likely drives the transport of ions such as calcium or other molecules across membranes. While the exact molecule ATP11A transports is unknown, increased expression of ATP11A mRNA has been observed in murine leukemia cells made resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs). Furthermore, overexpression of ATP11A provided protection against the FTI SCH66336 while knockdown of ATP11A via siRNA made cells more sensitive to this drug. Other reports suggest that elevated levels of ATP11A mRNA may also be a predictive marker of metastasis in colorectal cancer patients.Synonyms: ATPIH, ATPIS, ATPase IS, ATPase class VI type 11A, KIAA1021, Probable phospholipid-transporting ATPase IH

ID gène: 23250

NCBI Accession: NP_056020

UniProt: P98196