ZGPAT anticorps (C-Term)

N° du produit ABIN6991617

Détail du produit anti-ZGPAT anticorps

Antigène: ZGPAT (Zinc Finger, CCCH-Type with G Patch Domain (ZGPAT))

Épitope: C-Term

Reactivité: Humain

Hôte: Poulet

Clonalité: Polyclonal

Conjugué: Cet anticorp ZGPAT est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificité: Multiple isoforms of ZGPAT are known to exist.

Purification: ZGPAT Antibody is affinity chromatography purified via peptide column.

Immunogène: ZGPAT antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human ZGPAT. The immunogen is located within the last 50 amino acids of ZGPAT.

Isotype: IgY

Information d'application

Indications d'application: ZGPAT antibody can be used for detection of ZGPAT by Western blot at 1 μ,g/mL. Antibody can also be used for immunofluorescence starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: ZGPAT Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: ZGPAT antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur ZGPAT

Antigène: ZGPAT (Zinc Finger, CCCH-Type with G Patch Domain (ZGPAT))

Autre désignation: ZGPAT (ZGPAT Produits)

Synonymes: anticorps zc3h9, anticorps gpatc6, anticorps gpatch6, anticorps zc3hdc9, anticorps GPATC6, anticorps GPATCH6, anticorps KIAA1847, anticorps ZC3H9, anticorps ZC3HDC9, anticorps ZIP, anticorps 1500006I01Rik, anticorps BC021513, anticorps RGD1310801, anticorps zgc:63730, anticorps zinc finger CCCH-type and G-patch domain containing, anticorps zinc finger, CCCH-type with G-patch domain L homeolog, anticorps zinc finger, CCCH-type with G-patch domain, anticorps zinc finger, CCCH-type with G patch domain, anticorps ZGPAT, anticorps zgpat.L, anticorps zgpat, anticorps Zgpat

Sujet: ZGPAT Antibody: The Zinc finger CCCH-type with G patch domain-containing protein (ZGPAT), is a transcriptional repressor that regulates several cellular pathways including EGFR pathways that are involved in cell proliferation, migration and survival. ZGPAT recruits the Mi-2/NuRD complex and represses the expression of EGFR. ZGPAT is down-regulated in breast carcinomas and its expression is negatively correlated with that of EGFR, suggesting that it may be a potential target for breast cancer therapy. Multiple isoforms of ZGPAT are known to exist, including sZIP, which binds to the Mi-2/NuRD complex but lacks the DNA binding component of full-length ZGPAT, thereby antagonizing transcription repression and growth inhibition by ZGPAT.

ID gène: 84619

NCBI Accession: NP_115916

UniProt: Q8N5A5

Pathways: EGFR Signaling Pathway