CRIM1 anticorps (C-Term)

N° du produit ABIN6991727

Détail du produit anti-CRIM1 anticorps

Antigène: CRIM1 (Cysteine Rich Transmembrane BMP Regulator 1 (Chordin-Like) (CRIM1))

Épitope: AA 910-960, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRIM1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Specificité: CRIM1 antibody is human reactive. CRIM1 antibody is predicted to not cross-react with CRIM2.

Purification: CRIM1 Antibody is affinity chromatography purified via peptide column.

Immunogène: CRIM1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human Crim1. The immunogen is located within amino acids 910 - 960 of CRIM1.

Isotype: IgG

Information d'application

Indications d'application: CRIM1 antibody can be used for detection of Crim1 by Western blot at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: CRIM1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: CRIM1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CRIM1

Antigène: CRIM1 (Cysteine Rich Transmembrane BMP Regulator 1 (Chordin-Like) (CRIM1))

Autre désignation: CRIM1 (CRIM1 Produits)

Synonymes: anticorps CRIM1, anticorps AU015004, anticorps wu:fc29f08, anticorps CRIM-1, anticorps S52, anticorps cysteine rich transmembrane BMP regulator 1, anticorps cysteine rich transmembrane BMP regulator 1 (chordin like), anticorps cysteine rich transmembrane BMP regulator 1 (chordin-like), anticorps CRIM1, anticorps Crim1, anticorps crim1

Sujet: CRIM1 Antibody: CRIM1 (cysteine-rich motor neuron 1), a glycosylated type I transmembrane protein, plays a role in tissue development i.e. capillary formation and maintenance during angiogenesis. It contains an N-terminal IGF-binding protein-like motif and six von Willebrand-like cysteine-rich repeats (CRRs) in its extracellular domain. CRIM1 interacts with BMP4 and BMP7 via the CRRs and functions as an antagonist. CRIM1 is developmentally expressed in a number of tissues including the pancreas, kidney, placenta, brain and blood vessels. CRIM1 may participate in CNS and placental development by interacting with growth factors involved in motor neuron differentiation and survival.

ID gène: 51232

NCBI Accession: NP_057525

UniProt: Q9NZV1

Pathways: Growth Factor Binding