WIPI1 anticorps (C-Term)

N° du produit ABIN6991756

Détail du produit anti-WIPI1 anticorps

Antigène: WIPI1 (WD Repeat Domain, phosphoinositide Interacting 1 (WIPI1))

Épitope: AA 350-400, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WIPI1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificité: At least two isoforms of WIPI1 are known to exist, this antibody will detect both isoforms.

Purification: WIPI1 Antibody is affinity chromatography purified via peptide column.

Immunogène: WIPI1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human WIPI1. The immunogen is located within amino acids 350 - 400 of WIPI1.

Isotype: IgG

Information d'application

Indications d'application: WIPI1 antibody can be used for detection of Wipi1 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: WIPI1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: WIPI1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur WIPI1

Antigène: WIPI1 (WD Repeat Domain, phosphoinositide Interacting 1 (WIPI1))

Autre désignation: WIPI1 (WIPI1 Produits)

Synonymes: anticorps ATG18, anticorps ATG18A, anticorps WIPI49, anticorps 4930533H01Rik, anticorps AW411817, anticorps D11Ertd498e, anticorps RGD1307754, anticorps zgc:64205, anticorps WIPI1, anticorps atg18, anticorps wipi49, anticorps MGC145296, anticorps rgs9, anticorps wipi1, anticorps zgc:152760, anticorps WD repeat domain, phosphoinositide interacting 1, anticorps WD repeat domain, phosphoinositide interacting 1 S homeolog, anticorps regulator of G protein signaling 9a, anticorps WIPI1, anticorps Wipi1, anticorps wipi1, anticorps wipi1.S, anticorps rgs9a

Sujet: WIPI1 Antibody: WIPI1 (WD repeat domain, phosphoinositide interacting-1), also known as WIPI1, ATG18 or WIPI49, is thought to play a role in autophagy and may regulate protein trafficking in certain recycling pathways. It contains three WD repeats and has a 7-bladed propeller structure with a conserved motif that facilitates its interaction with other proteins. WIPI1 localizes to cytoplasmic vesicles, endosomes, clathrin-coated vesicles and the trans-Golgi network. It is ubiquitously expressed with highest expression in heart, testis, placenta, pancreas and skeletal muscle. WIPI1 is upregulated in a variety of tumors, suggesting a role in carcinogenesis.

Poids moléculaire: 49 kDa

ID gène: 55062

NCBI Accession: NP_060453

UniProt: Q5MNZ9

Pathways: Nuclear Hormone Receptor Binding, ER-Nucleus Signaling