APPBP2 antibody is human, mouse and rat reactive. At least two isoforms of APPBP2 are known to exist, this antibody will detect both isoforms.
Purification
APPBP2 antibody is affinity chromatography purified via peptide column.
Immunogène
APPBP2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human APPBP2. The immunogen is located within the last 50 amino acids of APPBP2.
APPBP2
Reactivité: Humain
WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
APPBP2 antibody can be used for detection of APPBP2 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
APPBP2 antibody is supplied in PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C,4 °C
Stockage commentaire
APPBP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Antigène
APPBP2
(Amyloid beta Precursor Protein (Cytoplasmic Tail) Binding Protein 2 (APPBP2))
anticorps HS.84084, anticorps PAT1, anticorps 1300003O07Rik, anticorps AI465480, anticorps zgc:76971, anticorps wu:fb78e11, anticorps wu:fc25c09, anticorps APPBP2, anticorps DKFZp459F0530, anticorps amyloid beta precursor protein binding protein 2, anticorps amyloid beta precursor protein (cytoplasmic tail) binding protein 2, anticorps amyloid beta precursor protein (cytoplasmic tail) binding protein 2 S homeolog, anticorps APPBP2, anticorps Appbp2, anticorps appbp2, anticorps appbp2.S
Sujet
The amyloid beta precursor protein (cytoplasmic tail) binding protein 2 (APPBP2), also known as PAT1, interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing (1). The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease (2). APPBP2 has been found to be highly expressed in breast cancer (3).