Sin Nombre Virus Glycoprotein 2 (AA 670-720) anticorps

N° du produit ABIN6991961

Détail du produit

Antigène: Sin Nombre Virus Glycoprotein 2

Épitope: AA 670-720

Reactivité: Sin Nombre Virus

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: ELISA

Purification: Sin Nombre virus glycoprotein 2 antibody is affinity chromatography purified via peptide column.

Immunogène: Sin Nombre virus glycoprotein 2 antibody was raised against a 16 amino acid peptide near the center of the Sin Nombre virus glycoprotein. The immunogen is located within amino acids 670 - 720 of Sin Nombre Virus Glycoprotein 2.

Isotype: IgG

Information d'application

Indications d'application: Sin Nombre virus glycoprotein 2 antibody can detect 10 ng Sin Nombre virus glycoprotein 2 peptide in ELISA at 1 μ,g/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Sin Nombre virus glycoprotein 2 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: Sin Nombre Glycoprotein 2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détail du antigène

Antigène: Sin Nombre Virus Glycoprotein 2

Classe de substances: Viral Protein

Sujet: Sin Nombre virus (SNV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS) (1). Hantavirus glycoprotein precursor (GPC) is posttranslationally cleaved into two glycoproteins G1 (Gn) and G2 (Gc). While the G1 glycoprotein is is thought to be degraded by the host autophagy machinery, and this autophagic clearance is required for efficient virus repliaction (2), no such degradation was observed for the G2 glycoprotein.

ID gène: 2654026

NCBI Accession: NP_941974

UniProt: Q89905