CRH anticorps (N-Term)
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- Antigène Voir toutes CRH Anticorps
- CRH (Corticotropin Releasing Hormone (CRH))
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Épitope
- AA 30-80, N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CRH est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Specificité
- CRH antibody is human specific.
- Purification
- CRH antibody is affinity chromatography purified via peptide column.
- Immunogène
- CRH antibody was raised against a 16 amino acid peptide near the amino terminus of human CRH. The immunogen is located within amino acids 30 - 80 of CRH.
- Isotype
- IgG
- Top Product
- Discover our top product CRH Anticorps primaire
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- Indications d'application
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CRH antibody can be used for detection of CRH by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- CRH antibody is supplied in PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,4 °C
- Stockage commentaire
- CRH antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- Antigène
- CRH (Corticotropin Releasing Hormone (CRH))
- Autre désignation
- CRH (CRH Produits)
- Synonymes
- anticorps CRF, anticorps Gm1347, anticorps crf, anticorps crh, anticorps zgc:101864, anticorps CRH, anticorps corticoliberin, anticorps crhb, anticorps crh.1-a, anticorps crha, anticorps corticotropin releasing hormone, anticorps corticotropin releasing hormone b, anticorps corticotropin releasing hormone S homeolog, anticorps corticotropin releasing hormone L homeolog, anticorps Crh, anticorps CRH, anticorps crhb, anticorps crh, anticorps crh.S, anticorps crh.L
- Sujet
- Corticotropin-releasing hormone (CRH) is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress (1). In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta where it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturitio (2). Marked reduction in this protein has been observed in association with Alzheimer disease (3).
- Poids moléculaire
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Predicted: 22 kDa
Observed: 29 kDa - ID gène
- 1392
- NCBI Accession
- NP_000747
- UniProt
- P06850
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Feeding Behaviour
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