XKR8 anticorps (C-Term)

N° du produit ABIN6992061

Détail du produit anti-XKR8 anticorps

Antigène: XKR8 (XK, Kell Blood Group Complex Subunit-Related Family, Member 8 (XKR8))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp XKR8 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: XKR8 antibody is human reactive. At least two isoforms are known to exist, this antibody will detect both isoforms.

Purification: XKR8 antibody is affinity chromatography purified via peptide column.

Immunogène: XKR8 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human XKR8. The immunogen is located within the last 50 amino acids of XKR8.

Isotype: IgG

Information d'application

Indications d'application: XKR8 antibody can be used for detection of XKR8 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: XKR8 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: XKR8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur XKR8

Antigène: XKR8 (XK, Kell Blood Group Complex Subunit-Related Family, Member 8 (XKR8))

Autre désignation: XKR8 (XKR8 Produits)

Synonymes: anticorps 4931440N07Rik, anticorps AI597014, anticorps Gm1031, anticorps XRG8, anticorps RP11-460I13.3, anticorps X-linked Kx blood group related 8, anticorps XK related 8, anticorps Xkr8, anticorps XKR8

Sujet: The XK Kell blood group complex subunit-related family member 8 (XKR8) is a member of a family of proteins that promote the phagocytosis of dying cells by altering the phospholipid distribution of the plasma membrane (1). XKR8 is thought to be a ""scramblase"", an enzyme that eliminates the asymmetry of phospholipid distribution in the plasma membrane. In apoptotic cells, XKR8 promotes the cell-surface exposure of phosphatidylserine (PtdSer) which serves as a signal for phagocytosis (1,2).

Poids moléculaire: Predicted: 43 kDa

Observed: 47 kDa

ID gène: 55113

NCBI Accession: NP_060523

UniProt: Q9H6D3