MCM6 anticorps

N° du produit ABIN7235301

L’anticorps anti-MCM6 Polyclonal Lapin est utilisé pour la détection de MCM6 dans des échantillons de Humain, Souris et Rat. Il a été validé pour IHC, WB et ELISA.

Aperçu rapide pour MCM6 anticorps (ABIN7235301)

Antigène: MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCM6 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Détail du produit anti-MCM6 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant protein of human MCM6

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MCM6

Antigène: MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))

Autre désignation: MCM6

Sujet: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.

Poids moléculaire: 93 kDa

UniProt: Q14566

Pathways: Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA