GADD45B anticorps

N° du produit ABIN7237053

Détail du produit anti-GADD45B anticorps

Antigène: GADD45B (Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GADD45B est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant protein of human GADD45B

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GADD45B

Antigène: GADD45B (Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))

Autre désignation: GADD45B (GADD45B Produits)

Synonymes: anticorps GADD45BETA, anticorps MYD118, anticorps AI323528, anticorps Myd118, anticorps CS131, anticorps cb196, anticorps gadd45b, anticorps gadd45b2, anticorps sb:cb196, anticorps zgc:73104, anticorps gadd45beta, anticorps wu:fa92d10, anticorps wu:fa98h12, anticorps wu:fk65h03, anticorps zgc:111973, anticorps gadd45b1, anticorps gadd45bl, anticorps zgc:112453, anticorps growth arrest and DNA damage inducible beta, anticorps growth arrest and DNA-damage-inducible 45 beta, anticorps growth arrest and DNA-damage-inducible, beta, anticorps growth arrest and DNA-damage-inducible, beta a, anticorps growth arrest and DNA-damage-inducible, beta b, anticorps GADD45B, anticorps Gadd45b, anticorps gadd45ba, anticorps gadd45bb

Sujet: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth.

UniProt: O75293

Pathways: Cycle Cellulaire