ITPR2 anticorps
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- Antigène Voir toutes ITPR2 Anticorps
- ITPR2 (Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ITPR2 est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC)
- Attributs du produit
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogène
- Synthetic peptide of human ITPR2
- Isotype
- IgG
- Top Product
- Discover our top product ITPR2 Anticorps primaire
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- Indications d'application
- IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.9 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- ITPR2 (Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2))
- Autre désignation
- ITPR2 (ITPR2 Produits)
- Synonymes
- anticorps AI649341, anticorps InsP3R-2, anticorps InsP3R-5, anticorps Ip3r2, anticorps Itpr5, anticorps insP3R2, anticorps IP3R2, anticorps inositol 1,4,5-trisphosphate receptor type 2, anticorps inositol 1,4,5-triphosphate receptor 2, anticorps inositol 1,4,5-trisphosphate receptor, type 2, anticorps ITPR2, anticorps Itpr2
- Sujet
- Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), which convert phosphatidylinositol-4,5 bisphosphate into IP3 and diacylglycerol (DAG). The inositol 1,4,5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3)-gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver.
- NCBI Accession
- NP_002214
- UniProt
- Q14571
- Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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