SFRP1 anticorps

N° du produit ABIN7242671

Détail du produit anti-SFRP1 anticorps

Antigène: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SFRP1 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human SFRP1

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100-1:300

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SFRP1

Antigène: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Autre désignation: SFRP1 (SFRP1 Produits)

Synonymes: anticorps FRP, anticorps FRP-1, anticorps FRP1, anticorps FrzA, anticorps SARP2, anticorps 2210415K03Rik, anticorps AW011917, anticorps AW107218, anticorps AW742929, anticorps sFRP-1, anticorps CSFRP1, anticorps SFRP1, anticorps XfrzA, anticorps frp, anticorps frp-1, anticorps frp1, anticorps frzA, anticorps sarp2, anticorps sfrp1, anticorps LOC100231868, anticorps Srfp1a, anticorps wu:fd19b09, anticorps secreted frizzled related protein 1, anticorps secreted frizzled-related protein 1, anticorps Secreted frizzled-related protein 1, anticorps secreted frizzled-related protein 1a, anticorps secreted frizzled-related protein 1b, anticorps SFRP1, anticorps Sfrp1, anticorps sfrp1, anticorps sfrp1a, anticorps sfrp1b

Sujet: This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling, epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.

NCBI Accession: NP_003003

UniProt: Q8N474

Pathways: Signalisation WNT, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation