anticorps STARD5, anticorps MGC131265, anticorps DKFZp469N2125, anticorps 2310058G22Rik, anticorps AI607880, anticorps D7Ertd152e, anticorps RGD1561783, anticorps StAR related lipid transfer domain containing 5, anticorps StAR related lipid transfer domain containing 5 S homeolog, anticorps StAR-related lipid transfer (START) domain containing 5, anticorps StAR-related lipid transfer domain containing 5, anticorps STARD5, anticorps stard5.S, anticorps Stard5
Sujet
Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1, MIM 184756) and by liver X receptors (e.g., LXRA, MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake.