EXD2 anticorps

N° du produit ABIN7246640

Détail du produit anti-EXD2 anticorps

Antigène: EXD2 (Exonuclease 3'-5' Domain Containing 2 (EXD2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EXD2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human EXD2

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.96 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur EXD2

Antigène: EXD2 (Exonuclease 3'-5' Domain Containing 2 (EXD2))

Autre désignation: EXD2 (EXD2 Produits)

Synonymes: anticorps C14orf114, anticorps EXDL2, anticorps 4930539P14Rik, anticorps C85658, anticorps Exdl2, anticorps RGD1311087, anticorps exd2-b, anticorps exdl2, anticorps fi72h12, anticorps wu:fi72h12, anticorps zgc:175195, anticorps exd2, anticorps exd2-a, anticorps exonuclease 3'-5' domain containing 2, anticorps exonuclease 3'-5' domain containing 2 b, anticorps EXD2, anticorps Exd2, anticorps exd2.S, anticorps exd2, anticorps exd2.L

Sujet: Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 70 kDa

UniProt: Q9NVH0