MAP3K7 anticorps (pThr187)
Aperçu rapide pour MAP3K7 anticorps (pThr187) (ABIN7250782)
Antigène
Voir toutes MAP3K7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- pThr187
-
Attributs du produit
- Phosphorylated antibody
-
Purification
- Affinity purification
-
Immunogène
- Synthesized peptide derived from human Tak1 around the phosphorylation site of Thr187
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))
-
Autre désignation
- MAP3K7
-
Sujet
- Component of a protein kinase signal transduction cascade. Mediator of TRAF6 and TGF-beta signal transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B.
-
Poids moléculaire
-
Observed_MW: 60 kDa
Calculated_MW: 67 kDa
-
UniProt
- O43318
-
Pathways
- Signalisation NF-kappaB, TCR Signaling, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway
Antigène
-