Meprin B anticorps

N° du produit ABIN7255141

Détail du produit anti-Meprin B anticorps

Antigène: Meprin B (MEP1B) (Meprin A, beta (MEP1B))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Meprin B est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human MEP1B (NP_005916.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Meprin B

Antigène: Meprin B (MEP1B) (Meprin A, beta (MEP1B))

Autre désignation: MEP1B (MEP1B Produits)

Synonymes: anticorps MEP1B, anticorps si:ch211-191a24.6, anticorps zgc:153272, anticorps Mep-1b, anticorps meprin A subunit beta, anticorps meprin A, beta, anticorps meprin 1 beta, anticorps MEP1B, anticorps LOC100031050, anticorps mep1b, anticorps LOC100545010, anticorps Mep1b

Sujet: Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine.

Poids moléculaire:

Observed_MW: 105 kDa

Calculated_MW: 79 kDa

ID gène: 4225

UniProt: Q16820