PNP anticorps

N° du produit ABIN7257591

Détail du produit anti-PNP anticorps

Antigène: PNP (NP) (Nucleoside Phosphorylase (NP))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PNP est non-conjugé

Application: Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human PNP (NP_000261.2).

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PNP

Antigène: PNP (NP) (Nucleoside Phosphorylase (NP))

Autre désignation: PNP (NP Produits)

Synonymes: anticorps NP, anticorps PRO1837, anticorps PUNP, anticorps Np, anticorps AL024301, anticorps AU015798, anticorps Np-1, anticorps Np-2, anticorps Pnp1, anticorps purine nucleoside phosphorylase, anticorps purine-nucleoside phosphorylase, anticorps PNP, anticorps Pnp

Classe de substances: Viral Protein

Sujet: This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2.

ID gène: 4860

UniProt: P00491

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Ribonucleoside Biosynthetic Process, Positive Regulation of Response to DNA Damage Stimulus