CYP2A6 anticorps

N° du produit ABIN7258314

Détail du produit anti-CYP2A6 anticorps

Antigène: CYP2A6 (Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP2A6 est non-conjugé

Application: Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human CYP2A6 (NP_000753.3).

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CYP2A6

Antigène: CYP2A6 (Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6))

Autre désignation: CYP2A6 (CYP2A6 Produits)

Synonymes: anticorps CPA6, anticorps CYP2A, anticorps CYP2A3, anticorps CYPIIA6, anticorps P450C2A, anticorps P450PB, anticorps cyp2a6, anticorps cytochrome P450 family 2 subfamily A member 6, anticorps cytochrome P450 2A6, anticorps cytochrome P450 family 2 subfamily A member 6 L homeolog, anticorps CYP2A6, anticorps cyp2a6.L

Sujet: This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3, however, it has been renamed CYP2A6.

ID gène: 1548

UniProt: P11509