NR1I2 anticorps
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- Antigène Voir toutes NR1I2 Anticorps
- NR1I2 (Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NR1I2 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Attributs du produit
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human PXR
- Isotype
- IgG
- Top Product
- Discover our top product NR1I2 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000 IF 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- NR1I2 (Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2))
- Autre désignation
- PXR (NR1I2 Produits)
- Synonymes
- anticorps BXR, anticorps ONR1, anticorps PAR, anticorps PAR1, anticorps PAR2, anticorps PARq, anticorps PRR, anticorps PXR, anticorps SAR, anticorps SXR, anticorps PXR.1, anticorps PXR.2, anticorps PXR1, anticorps mPXR, anticorps bxr, anticorps nr1i2, anticorps onr1, anticorps xonr1, anticorps nuclear receptor subfamily 1 group I member 2, anticorps nuclear receptor subfamily 1, group I, member 2, anticorps nuclear receptor subfamily 1 group I member 2 S homeolog, anticorps NR1I2, anticorps Nr1i2, anticorps nr1i2.S, anticorps nr1i2
- Sujet
- This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized.
- Poids moléculaire
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Observed_MW: 50 kDa
Calculated_MW: 50 kDa
- ID gène
- 8856
- UniProt
- O75469
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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