MPG anticorps

N° du produit ABIN7009745

Détail du produit anti-MPG anticorps

Antigène: MPG (N-Methylpurine-DNA Glycosylase (MPG))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MPG est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody ist KO validated.

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Classe de qualité: KO Validated

Immunogène: Recombinant fusion protein of human MPG (NP_001015052.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MPG

Antigène: MPG (N-Methylpurine-DNA Glycosylase (MPG))

Autre désignation: MPG (MPG Produits)

Synonymes: anticorps AAG, anticorps ADPG, anticorps APNG, anticorps CRA36.1, anticorps MDG, anticorps Mid1, anticorps PIG11, anticorps PIG16, anticorps anpg, anticorps 9830006D05, anticorps AI326268, anticorps Aag, anticorps zgc:162984, anticorps si:xx-187g17.9, anticorps MPG, anticorps MPGR, anticorps N-methylpurine DNA glycosylase, anticorps N-methylpurine-DNA glycosylase, anticorps si:xx-by187g17.9, anticorps MPG, anticorps Mpg, anticorps mpg, anticorps si:xx-by187g17.9, anticorps CpB0526, anticorps gll2491

Sujet: Maintenance of DNA sequences is necessary for vertebrates and other life. DNA is under constant stress by a plethora of DNA-damaging agents present in both the environment and within cells. The potentially deleterious effects of DNA lesions in cells are elegantly resolved by sophisticated DNA repair systems, including base excision repair (BER), nucleotide excision repair (NER) and DNA repair methyltransferase (MTase). Methylated bases, such as 3-methyladenine (3MeA) and 7-methylguanine (7MeG) can be formed by agents in the environment and by endogenous cellular processes. Consequently, in the absence of exposure to environmental agents, DNA methylation damage can be incurred on the genomic DNA of normal mammalian cells. DNA N-glycosylases are base excision-repair proteins that locate and cleave damaged bases from DNA as the first step in restoring the sequence.

Poids moléculaire:

Observed_MW: 37 kDa

Calculated_MW: 30 kDa/32 kDa

ID gène: 4350

UniProt: P29372

Pathways: Réparation de l'ADN