Prosaposin anticorps

N° du produit ABIN7259801

Détail du produit anti-Prosaposin anticorps

Antigène: Prosaposin (PSAP)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Prosaposin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human PSAP (NP_002769.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Prosaposin

Antigène: Prosaposin (PSAP)

Autre désignation: PSAP (PSAP Produits)

Synonymes: anticorps GLBA, anticorps SAP1, anticorps AI037048, anticorps SGP-1, anticorps SGP1A, anticorps cb759, anticorps wu:fa14a06, anticorps wu:fb36e02, anticorps wu:fb58g07, anticorps PSAP, anticorps PSP-A, anticorps SFTPA1B, anticorps SP-A, anticorps prosaposin, anticorps surfactant protein A1, anticorps PSAP, anticorps Psap, anticorps psap, anticorps LOC100011417, anticorps LOC100304726, anticorps LOC100526719, anticorps SFTPA1

Sujet: This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Poids moléculaire:

Observed_MW: 58 kDa

Calculated_MW: 58 kDa

ID gène: 5660

UniProt: P07602

Pathways: Positive Regulation of Endopeptidase Activity