PDHA1 anticorps

N° du produit ABIN7259915

Détail du produit anti-PDHA1 anticorps

Antigène: PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDHA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human PDHA1 (NP_000275.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PDHA1

Antigène: PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))

Autre désignation: PDHA1 (PDHA1 Produits)

Synonymes: anticorps PDHA, anticorps PDHCE1A, anticorps PHE1A, anticorps Pdha-1, anticorps pdha, anticorps phe1a, anticorps pdhce1a, anticorps im:6895726, anticorps pdha1, anticorps wu:fd18b01, anticorps wu:fo96f03, anticorps zgc:73271, anticorps zgc:86692, anticorps Pdha1, anticorps wu:fp73b04, anticorps zgc:92705, anticorps NI36_05250, anticorps pdha1-a, anticorps pdha1-b, anticorps pyruvate dehydrogenase E1 alpha 1 subunit, anticorps pyruvate dehydrogenase E1 alpha 1, anticorps pyruvate dehydrogenase (lipoamide) alpha 1, anticorps pyruvate dehydrogenase (lipoamide) alpha 1 pseudogene, anticorps 2-oxo acid dehydrogenase, anticorps pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha, anticorps pyruvate dehydrogenase alpha subunit protein, anticorps pyruvate dehydrogenase (acetyl-transferring) protein, alpha subunit, anticorps precursor of dehydrogenase pyruvate dehydrogenase E1 component alpha subunit, anticorps pyruvate dehydrogenase, anticorps pyruvate dehydrogenase E1 alpha 1 subunit a, anticorps pyruvate dehydrogenase E1 alpha 1 subunit b, anticorps pyruvate dehydrogenase E1 component subunit alpha, anticorps pyruvate dehydrogenase (lipoamide) alpha 1 S homeolog, anticorps PDHA1, anticorps Pdha1, anticorps pdha1, anticorps LOC719277, anticorps VNG_RS07485, anticorps RR_RS04695, anticorps pdhA1, anticorps pdha1a, anticorps pdha1b, anticorps NI36_RS05240, anticorps pdha1.S

Sujet: The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire:

Observed_MW: 45 kDa

Calculated_MW: 40 kDa/43 kDa/44 kDa/47 kDa

ID gène: 5160

UniProt: P08559

Pathways: L'effet Warburg