LITAF anticorps

N° du produit ABIN7261431

Détail du produit anti-LITAF anticorps

Antigène: LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LITAF est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: This antibody ist KO validated.

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Classe de qualité: KO Validated

Immunogène: Recombinant fusion protein of human LITAF (NP_004853.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur LITAF

Antigène: LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))

Autre désignation: LITAF (LITAF Produits)

Synonymes: anticorps PIG7, anticorps SIMPLE, anticorps TP53I7, anticorps EET-1, anticorps Pig7, anticorps TNF-alpha, anticorps 3222402J11Rik, anticorps C85531, anticorps N4WBP3, anticorps TBX1, anticorps lipopolysaccharide induced TNF factor, anticorps lipopolysaccharide-induced TNF factor, anticorps LPS-induced TN factor, anticorps LITAF, anticorps Litaf

Sujet: Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene.

Poids moléculaire:

Observed_MW: 20 kDa

Calculated_MW: 15 kDa/17 kDa/23 kDa

ID gène: 9516

UniProt: Q99732

Pathways: Cellular Response to Molecule of Bacterial Origin