RFC4 anticorps

N° du produit ABIN7261451

Détail du produit anti-RFC4 anticorps

Antigène: RFC4 (Replication Factor C (Activator 1) 4, 37kDa (RFC4))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RFC4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human RFC4 (NP_002907.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RFC4

Antigène: RFC4 (Replication Factor C (Activator 1) 4, 37kDa (RFC4))

Autre désignation: RFC4 (RFC4 Produits)

Synonymes: anticorps 44.t00003, anticorps 21.m03053, anticorps rfc4, anticorps A1, anticorps AI894123, anticorps AU040575, anticorps RFC37, anticorps rfc2, anticorps replication factor C subunit 4, anticorps Replication factor C subunit 4, anticorps replication factor C (activator 1) 4, anticorps replication factor C subunit 4 L homeolog, anticorps PFL2005w, anticorps EHI_167150, anticorps TP03_0432, anticorps Tb11.01.1310, anticorps BBOV_IV002210, anticorps rfc4, anticorps rfc-4, anticorps Rfc4, anticorps RFC4, anticorps rfc4.L

Sujet: The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.

Poids moléculaire:

Observed_MW: 40 kDa

Calculated_MW: 33 kDa/39 kDa

ID gène: 5984

UniProt: P35249

Pathways: Telomere Maintenance, Réparation de l'ADN, DNA Replication, Synthesis of DNA