PTPN18 anticorps
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- Antigène Voir toutes PTPN18 Anticorps
- PTPN18 (Protein tyrosine Phosphatase, Non-Receptor Type 18 (Brain-Derived) (PTPN18))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PTPN18 est non-conjugé
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Application
- Western Blotting (WB)
- Attributs du produit
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein of human PTPN18 (NP_001135842.1).
- Isotype
- IgG
- Top Product
- Discover our top product PTPN18 Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- PTPN18 (Protein tyrosine Phosphatase, Non-Receptor Type 18 (Brain-Derived) (PTPN18))
- Autre désignation
- PTPN18 (PTPN18 Produits)
- Synonymes
- anticorps BDP1, anticorps PTP-HSCF, anticorps FLP1, anticorps HSCF, anticorps PTP-K1, anticorps Ptpk1, anticorps PTP20, anticorps protein tyrosine phosphatase, non-receptor type 18, anticorps PTPN18, anticorps Ptpn18
- Sujet
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene.
- Poids moléculaire
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Observed_MW: 60 kDa
Calculated_MW: 38 kDa/50 kDa
- ID gène
- 26469
- UniProt
- Q99952
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