MCTS1 anticorps

N° du produit ABIN7264733

Détail du produit anti-MCTS1 anticorps

Antigène: MCTS1 (Malignant T Cell Amplified Sequence 1 (MCTS1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCTS1 est non-conjugé

Application: Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human MCTS1 (NP_054779.1).

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MCTS1

Antigène: MCTS1 (Malignant T Cell Amplified Sequence 1 (MCTS1))

Autre désignation: MCTS1 (MCTS1 Produits)

Synonymes: anticorps MCT-1, anticorps MCT1, anticorps MCT1a, anticorps cb517, anticorps zgc:55682, anticorps 1500019M23Rik, anticorps zgc:56242, anticorps mcts1, anticorps MGC89874, anticorps MCTS1, anticorps MCT-1A, anticorps mct-1, anticorps mct1, anticorps MCT-1B, anticorps mcts1-a, anticorps mcts1-b, anticorps MCTS1, re-initiation and release factor, anticorps solute carrier family 16 (monocarboxylate transporter), member 1b, anticorps malignant T cell amplified sequence 1, anticorps malignant T-cell amplified sequence 1, anticorps solute carrier family 16 member 1, anticorps malignant T-cell amplified sequence 1 S homeolog, anticorps monocarboxylate transporter 1, anticorps malignant T-cell amplified sequence 1 L homeolog, anticorps MCTS1, anticorps slc16a1b, anticorps Mcts1, anticorps mcts1, anticorps SLC16A1, anticorps mcts1.S, anticorps MCT1, anticorps mcts1.L

Sujet: MCTS1 (malignant T cell amplified sequence 1), also known as MCT1, is a 181 amino acid protein that is ubiquitously expressed and localizes to the cytoplasm of cells. MCTS1 may play a role in cell cycle regulation by decreasing cell doubling time and by shortening the duration of G1 transit time and G1/S transition. The protein level of Cdk4 and Cdk6 kinases activity and cyclin D1 is enhanced by expression of MCTS1. As a translation enhancer, MCTS1 recruits DENR and binds to the cap complex of the 5'-terminus of mRNAs, subsequently altering the mRNA translation profile. MCTS1 promotes lymphoid tumor development and contributes to the pathogenesis and progression of breast cancer. MCTS1 positively regulates phosphorylation of ERK1 and ERK2.

ID gène: 28985

UniProt: Q9ULC4