ZAP70 anticorps (pTyr493)

N° du produit ABIN7265210

Cet anticorps anti-ZAP70 est un anticorps Lapin Polyclonal détectant ZAP70 dans WB et IHC. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour ZAP70 anticorps (pTyr493) (ABIN7265210)

Antigène: ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZAP70 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-ZAP70 anticorps

Épitope: pTyr493

Attributs du produit: Phosphorylated antibody

Purification: Affinity purification

Immunogène: A phospho specific peptide corresponding to residues surrounding Y493 of human ZAP70

Isotype: IgG

Information d'application

Indications d'application: WB 1:2000-1:5000 IHC 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ZAP70

Antigène: ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

Autre désignation: ZAP70

Sujet: This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.

Poids moléculaire:

Observed_MW: 70 kDa

Calculated_MW: 35 kDa/55 kDa/69 kDa

ID gène: 7535

UniProt: P43403

Pathways: TCR Signaling, Ubiquitin Proteasome Pathway