GZMB anticorps (FITC)
-
- Antigène Voir toutes GZMB Anticorps
- GZMB (Granzyme B (GZMB))
-
Reactivité
- Humain, Non-Human Primate
-
Hôte
- Souris
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp GZMB est conjugé à/à la FITC
-
Application
- Flow Cytometry (FACS)
- Specificité
- The mouse monoclonal antibody CLB-GB11 recognizes granzyme B, a 31 kDa serine protease expressed intracellularly in activated Tc cells and NK cells.
- Purification
- Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Immunogène
- Human NK cell line YT-INDY-derived granzyme B
- Clone
- CLB-GB11
- Isotype
- IgG1
- Top Product
- Discover our top product GZMB Anticorps primaire
-
anti-Granzyme B (GZMB) (AA 21-247) antibody
GZMB Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 73-187) antibodyGZMB Reactivité: Humain WB, IHC, StM Hôte: Souris Monoclonal GZMB-3014 unconjugated
anti-Granzyme B (GZMB) antibodyGZMB Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal CLB-GB11 unconjugated
anti-Granzyme B (GZMB) (AA 21-130) antibodyGZMB Reactivité: Humain, Souris WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 175-203), (C-Term) antibodyGZMB Reactivité: Humain WB, FACS, IHC (p) Hôte: Lapin Polyclonal RB19353 unconjugated
anti-Granzyme B (GZMB) (AA 21-247) antibodyGZMB Reactivité: Humain WB, IHC, ELISA Hôte: Souris Monoclonal 2G12G7 unconjugated
anti-Granzyme B (GZMB) (AA 1-247) antibodyGZMB Reactivité: Humain WB, IP Hôte: Lapin Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 73-187) antibodyGZMB Reactivité: Humain IHC, StM Hôte: Souris Monoclonal GZMB-3056 unconjugated
anti-Granzyme B (GZMB) antibodyGZMB Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 21-247) antibodyGZMB Reactivité: Humain WB, IHC, IF, IHC (p) Hôte: Souris Monoclonal 4E4 unconjugated
-
- Indications d'application
- Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. Intracellular staining.
- Restrictions
- For Research Use only
-
- Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
-
- Antigène
- GZMB (Granzyme B (GZMB))
- Autre désignation
- Granzyme B (GZMB Produits)
- Synonymes
- anticorps CCPI, anticorps CGL-1, anticorps CGL1, anticorps CSP-B, anticorps CSPB, anticorps CTLA1, anticorps CTSGL1, anticorps HLP, anticorps SECT, anticorps granzyme B, anticorps GZMB
- Sujet
- Granzyme B,Granzyme B is a serine protease that is expressed in cytoplasmic granules of cytotoxic T lymphocytes and NK cells. Vectorial secretion of perforin and granzymes is responsible for their granule-mediated cytotoxicity. Granzyme B plays a pivotal role in the induction of apoptosis in the target cells by activation of caspases. Moreover, granzyme B was reported to cleave directly alpha-tubulin, leading to perturbation of microtubule networks during the induced cell death.,GZMB, HLP, CTLA1, SECT
- ID gène
- 3002
- UniProt
- P10144
- Pathways
- Apoptose, Caspase Cascade in Apoptosis
-
