anticorps RGD1310159, anticorps 2410021P16Rik, anticorps acyl-CoA dehydrogenase family, member 10, anticorps acyl-CoA dehydrogenase family member 10, anticorps acyl-CoA dehydrogenase family member 10 L homeolog, anticorps acyl-Coenzyme A dehydrogenase family, member 10, anticorps Acad10, anticorps ACAD10, anticorps LOC588060, anticorps acad10.L, anticorps acad10, anticorps LOC100179340, anticorps LOC100632488
Sujet
This gene encodes a member of the acyl-CoA dehydrogenase family of enzymes (ACADs), which participate in the beta-oxidation of fatty acids in mitochondria. The encoded enzyme contains a hydrolase domain at the N-terminal portion, a serine/threonine protein kinase catlytic domain in the central region, and a conserved ACAD domain at the C-terminus. ACAD10 has significant activity towards the branched-chain substrates R and S, 2 methyl-C15-CoA and is highly expressed in fetal but not adult brain. This pattern of expression is similar to that of LCAD, another ACAD previously shown to be involved in long branched chain fatty acid metabolism.