alpha Actinin anticorps

N° du produit ABIN7073024

Détail du produit anti-alpha Actinin anticorps

Antigène: alpha Actinin (ACTN) (alpha-Actinin Skeletal Muscle (ACTN))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp alpha Actinin est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain, Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse alpha-actinin1

Information d'application

Indications d'application: WB (H,M,R) 1:2000-1:4000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur alpha Actinin

Antigène: alpha Actinin (ACTN) (alpha-Actinin Skeletal Muscle (ACTN))

Autre désignation: alpha Actinin (ACTN Produits)

Synonymes: anticorps actinin, alpha 4, anticorps alpha-actinin, anticorps ACTN4, anticorps ain1

Sujet: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found alongmicrofilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene.

Poids moléculaire: 103 kDa

ID gène: 109711

NCBI Accession: NP_598917

UniProt: Q7TPR4

Pathways: Cell-Cell Junction Organization, Negative Regulation of Transporter Activity