NG2 anticorps

N° du produit ABIN7074588

Détail du produit anti-NG2 anticorps

Antigène: NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NG2 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse NG2

Information d'application

Indications d'application: WB (M,R) 1:300-1:600

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur NG2

Antigène: NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))

Autre désignation: NG2 (MCSP Produits)

Synonymes: anticorps HMW-MAA, anticorps MCSP, anticorps MCSPG, anticorps MEL-CSPG, anticorps MSK16, anticorps NG2, anticorps 4732461B14Rik, anticorps AN2, anticorps Ng2, anticorps HSMCSGEN1, anticorps MCS, anticorps chondroitin sulfate proteoglycan 4, anticorps sperm mitochondria associated cysteine rich protein, anticorps CSPG4, anticorps Cspg4, anticorps SMCP

Sujet: CSPG4, also named as HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16 and NG2, is a proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. CSPG4 may inhibit neurite outgrowth and growth cone collapse during axon regeneration. It is cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. CSPG4 may regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. It modulates the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin.

Poids moléculaire: 252 kDa

ID gène: 121021

NCBI Accession: NP_620570

UniProt: Q8VHY0

Pathways: Glycosaminoglycan Metabolic Process