MLK4 anticorps
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- Antigène Voir toutes MLK4 (KIAA1804) Anticorps
- MLK4 (KIAA1804) (Mitogen-Activated Protein Kinase Kinase Kinase MLK4 (KIAA1804))
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Reactivité
- Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MLK4 est non-conjugé
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Application
- Western Blotting (WB)
- Réactivité croisée
- Rat
- Purification
- Affinity purification
- Immunogène
- Recombinant protein corresponding to Mouse MLK4
- Top Product
- Discover our top product KIAA1804 Anticorps primaire
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- Indications d'application
- WB (M,R) 1: 500-1: 1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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- Antigène
- MLK4 (KIAA1804) (Mitogen-Activated Protein Kinase Kinase Kinase MLK4 (KIAA1804))
- Autre désignation
- MLK4 (KIAA1804 Produits)
- Synonymes
- anticorps MLK4, anticorps RP5-862P8.2, anticorps dJ862P8.3, anticorps Mlk4, anticorps mKIAA1804, anticorps mitogen-activated protein kinase kinase kinase 21, anticorps MAP3K21, anticorps Map3k21
- Sujet
- MLK4 belongs to the MAP kinase subfamily. The MLK family members are characterized by the presence of signature sequences of Ser/Thr and Tyr kinases within their catalytic domain. The MLK1-4 contains an aminoterminal Src-Homology (SH3) domain, followed by the kinase domain, a leucine-zipper region, and a Cdc42/Rac-interactive binding (CRIB) motif. MLK4 expressed in two splicing variants, MLK4α and MLK4β. The difference of these two isoforms is located in their C-terminal portion. The negative effect of MLK4 on LPS-induced ERK and JNK activation could be very important in controlling the level of cytokine expression, and thus maintaining the balance of inflammatory responses.
- Poids moléculaire
- 120 kDa
- ID gène
- 234878
- NCBI Accession
- NP_663583
- UniProt
- Q8VDG6
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