Nectin-1 (NECTIN1) anticorps

N° du produit ABIN7074789

Détail du produit

Antigène: Nectin-1 (NECTIN1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB)

Réactivité croisée: Humain

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse PVRL1/NECTIN1

Information d'application

Indications d'application: WB (H) 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détail du antigène

Antigène: Nectin-1 (NECTIN1)

Autre désignation: PVRL1/NECTIN1

Synonymes: anticorps CD111, anticorps CLPED1, anticorps ED4, anticorps HIgR, anticorps HVEC, anticorps OFC7, anticorps PRR, anticorps PRR1, anticorps PVRR, anticorps PVRR1, anticorps SK-12, anticorps nectin-1, anticorps nectin cell adhesion molecule 1, anticorps NECTIN1

Sujet: This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain, and a cytoplasmic region. This protein acts as a receptor for glycoprotein D of herpes simplex viruses 1 and 2, and pseudorabies virus and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome as well as non-syndromic cleft lip with or without cleft palate.

Poids moléculaire: 57 kDa

ID gène: 58235

NCBI Accession: NP_067399

UniProt: Q9JKF6