Nth Endonuclease III-Like 1 (NTHL1) anticorps

N° du produit ABIN7074866

Détail du produit

Antigène: Nth Endonuclease III-Like 1 (NTHL1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB)

Réactivité croisée: Humain

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse NTH1

Information d'application

Indications d'application: WB (H) 1:1000-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détail du antigène

Antigène: Nth Endonuclease III-Like 1 (NTHL1)

Autre désignation: NTH1 (NTHL1 Produits)

Synonymes: anticorps psmc3, anticorps psmc3-a, anticorps nth-like DNA glycosylase 1 S homeolog, anticorps nthl1.S

Sujet: NTHL1, also named as Endonuclease III-like protein 1 or OCTS3, is a 312 amino acid protein, which belongs to the Nth/MutY family. NTHL1 localizes in the nucleus and is widely expressed with highest levels in heart and lowest levels in lung and liver. NTHL1 Has both an apurinic and/or apyrimidinic endonuclease activity and a DNA N-glycosylase activity and incises damaged DNA at cytosines, thymines and guanines. NTHL1 acts on a damaged strand, 5' from the damaged site and is required for the repair of both oxidative DNA damage and spontaneous mutagenic lesions.

Poids moléculaire: 34 kDa

ID gène: 18207

NCBI Accession: NP_032769

UniProt: O35980