anticorps RGD1311563, anticorps 1300006C19Rik, anticorps Simp, anticorps SIMP, anticorps STT3-B, anticorps STT3B, catalytic subunit of the oligosaccharyltransferase complex, anticorps STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae), anticorps Stt3b, anticorps STT3B
Sujet
STT3B is a component of the N-oligosaccharyl transferase (OST) enzyme which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). SST3B seems to be involved in complex substrate specificity.