TBC1D17 anticorps

N° du produit ABIN7075844

Détail du produit anti-TBC1D17 anticorps

Antigène: TBC1D17 (TBC1 Domain Family, Member 17 (TBC1D17))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TBC1D17 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain, Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse TBC1D17

Information d'application

Indications d'application: WB (H,R) 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur TBC1D17

Antigène: TBC1D17 (TBC1 Domain Family, Member 17 (TBC1D17))

Autre désignation: TBC1D17 (TBC1D17 Produits)

Synonymes: anticorps BC017607, anticorps TBC1 domain family member 17, anticorps TBC1 domain family, member 17, anticorps TBC1D17, anticorps Tbc1d17

Sujet: Probable GTPase-activating protein for Rab8, its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transferrin receptor (TfR) and reduces Rab8 recruitnment to tubules emanating from the endocytic recycling compartment (ERC). Involved in regulation of autophagy. Mediates inhibition of autophagy caused by the OPTN variant GLC1E LYS-50, the function requires its catalytic activity, however, the involved Rab is not known.

Poids moléculaire: 73 kDa

ID gène: 233204

NCBI Accession: NP_001036120

UniProt: Q8BYH7