TTC7A anticorps

N° du produit ABIN7075875

Détail du produit anti-TTC7A anticorps

Antigène: TTC7A (Tetratricopeptide Repeat Domain 7A (TTC7A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TTC7A est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse TTC7A

Information d'application

Indications d'application: WB (H) 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur TTC7A

Antigène: TTC7A (Tetratricopeptide Repeat Domain 7A (TTC7A))

Autre désignation: TTC7A (TTC7A Produits)

Synonymes: anticorps 1110035E02Rik, anticorps 1700007L07Rik, anticorps Ttc7a, anticorps fsn, anticorps hea, anticorps MINAT, anticorps TTC7, anticorps Ttc7, anticorps tetratricopeptide repeat domain 7, anticorps tetratricopeptide repeat domain 7A, anticorps Ttc7, anticorps TTC7A, anticorps Ttc7a

Sujet: TTC7A (TPR repeat protein 7A) is expressed in enterocytes within the duodenum, ileum, and colon, and has a role in enterocyte survival and function. Mutations in the TTC7A gene can result in a spectrum of intestinal disease, including multiple intestinal atresia (MIA) and very early onset inflammatory bowel diseases (VEOIBD). Functional analysis revealed that TTC7A binds to and facilitates the transport of PI4KIIIa from the trans-Golgi to the plasma membrane, while loss of TTC7A results in dysregulation of PI4KIIIa signaling. This antibody specially recognizes endogenous TTC7A.

Poids moléculaire: 100 kDa

ID gène: 225049

NCBI Accession: NP_082915

UniProt: Q8BGB2

Pathways: Transition Metal Ion Homeostasis