TAB3 anticorps

N° du produit ABIN7075877

Détail du produit anti-TAB3 anticorps

Antigène: TAB3 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TAB3 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse TAB3

Information d'application

Indications d'application: WB (M,R) 1: 500-1: 1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur TAB3

Antigène: TAB3 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))

Autre désignation: TAB3 (TAB3 Produits)

Synonymes: anticorps MAP3K7IP3, anticorps NAP1, anticorps 4921526G09Rik, anticorps Map3k7ip3, anticorps mKIAA4135, anticorps map3k7ip3, anticorps nap1, anticorps tab3, anticorps tab3-a, anticorps tab3-b, anticorps map3k7ip3l, anticorps si:ch211-232d19.8, anticorps si:dkey-30h22.6, anticorps TGF-beta activated kinase 1 and MAP3K7 binding protein 3, anticorps TGF-beta activated kinase 1/MAP3K7 binding protein 3, anticorps TGF-beta activated kinase 1/MAP3K7 binding protein 3 S homeolog, anticorps TAB3, anticorps Tab3, anticorps tab3.S, anticorps tab3

Sujet: Mitogen-activated protein kinase 7-interacting protein 3 is an enzyme encoded by the MAP3K7IP3 gene. The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2 TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Poids moléculaire: 79 kDa

ID gène: 66724

NCBI Accession: NP_080005

UniProt: Q571K4

Pathways: Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades