TOR1AIP2 anticorps

N° du produit ABIN7075941

Détail du produit anti-TOR1AIP2 anticorps

Antigène: TOR1AIP2 (Torsin A Interacting Protein 2 (TOR1AIP2))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TOR1AIP2 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse TOR1AIP2

Information d'application

Indications d'application: WB (M,R) 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur TOR1AIP2

Antigène: TOR1AIP2 (Torsin A Interacting Protein 2 (TOR1AIP2))

Autre désignation: TOR1AIP2 (TOR1AIP2 Produits)

Synonymes: anticorps IFRG15, anticorps LULL1, anticorps NET9, anticorps RP11-12M5.5, anticorps 1110020D10Rik, anticorps 15kDa, anticorps A130072J07, anticorps AA103493, anticorps AW060462, anticorps AW610675, anticorps C77739, anticorps Ifrg15, anticorps Lull1, anticorps torsin 1A interacting protein 2, anticorps torsin-1A-interacting protein 2, anticorps torsin A interacting protein 2, anticorps torsin-1A-interacting protein 2, isoform IFRG15, anticorps TOR1AIP2, anticorps LOC610310, anticorps LOC100050862, anticorps LOC100338750, anticorps LOC100385418, anticorps LOC100595243, anticorps Tor1aip2

Sujet: LULL1 is a 470 amino acid endoplasmic reticulum single-pass membrane protein belonging to the TOR1AIP family. LULL1 interacts with torsinA, an essential AAA+ ATPase found in the endoplasmic reticulum (ER) and nuclear envelope (NE) of higher eukaryotes. LULL1 regulates the distribution and activity of torsinA within the ER and NE lumen and reveals functional defects in mutant torsinA, which is responsible for DYT1 dystonia, a neurodevelopmental disease caused by an in-frame deletion (Deltagag) in the gene encoding torsinA. The gene encoding LULL1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8 % of the human genome.

Poids moléculaire: 58 kDa

ID gène: 240832

NCBI Accession: NP_001153652

UniProt: Q9ER81