TFG anticorps

N° du produit ABIN7076022

Détail du produit anti-TFG anticorps

Antigène: TFG (Trk-Fused Gene (TFG))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TFG est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Human TRK fused gene

Information d'application

Indications d'application: WB (H) 1:500- 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur TFG

Antigène: TFG (Trk-Fused Gene (TFG))

Autre désignation: TRK fused gene (TFG Produits)

Synonymes: anticorps wu:fb11c10, anticorps zgc:55342, anticorps zgc:77230, anticorps HMSNP, anticorps SPG57, anticorps TF6, anticorps TRKT3, anticorps AI173908, anticorps trk-fused gene, anticorps TRK-fused gene, anticorps Trk-fused gene, anticorps tfg, anticorps TFG, anticorps Tfg

Sujet: Protein TFG (TRK-fused gene protein) plays a role in regulating phosphotyrosine-specific phosphatase-1 activity. Mutations in TFG may have important clinical relevance for current therapeutic strategies to treat metastatic melanoma. Defects in TFG are a cause of thyroid papillary carcinoma (TPC), a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Recent genetic investigation indicates that formation of TFG-containing cytoplasmic inclusions and concomitant mislocalization of TAR DNA-binding protein 43 kDa (TDP-43) underlie motor neuron degeneration in HMSN-P. Pathological overlap of proteinopathies involving TFG and TDP-43 highlights a new pathway leading to motor neuron degeneration.

Poids moléculaire: 55 kDa

ID gène: 10342

UniProt: Q92734