ZAP70 anticorps (AA 247-382) (FITC)

N° du produit ABIN7076784

Cet anticorps Souris Monoclonal détecte spécifiquement ZAP70 dans FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour ZAP70 anticorps (AA 247-382) (FITC) (ABIN7076784)

Antigène: ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ZAP70 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Classe de qualité: GMP Grade (Analyte)

Clone: C-D12

Détail du produit anti-ZAP70 anticorps (FITC)

Épitope: AA 247-382

Fonction: Zap70 FITC Antibody

Attributs du produit: The clone C-D12, a mouse monoclonal antibody selectively binds with the 70kd tyrosine phosphoprotein known as ZAP-70 which is usually associated with the ζ-chain CD3-receptor-associated protein tyrosine kinase (PTK). It is a member of the Syk family that is localized exclusively to the cytosol of T cells and natural killer (NK) cells and  is required for their cellular activation. It is generally considered the T-lymphocyte counterpart of Syk, a B-cell receptor (BCR)-associated kinase that belongs to the same PTK family and plays a similar role in the antigen receptor signaling in the B-lineage cells. It facilitates the upregulation of Fas ligand in activation-induced T cell apoptosis. ZAP-70 expression plays an important role in the clinical diagnosis of various types of hematologic malignancies.

Purification: Purified

Pureté: >95 %

Immunogène: Recombinant fragment of human ZAP70 protein (around aa 247-382)

Isotype: IgG1, kappa

Information d'application

Indications d'application: FC: 5 µL/test We recommend that every lab carries out an initial titration study before running your samples to ensure that the optimal concentration is selected for your application.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.2, 0.09 % Sodium azide and 0.2 % (w/v) BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: 2-8°C, Conjugated antibodies should never be frozen.

Détails sur ZAP70

Antigène: ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

Autre désignation: Zap70

ID gène: 7535

UniProt: P43403

Pathways: TCR Signaling, Ubiquitin Proteasome Pathway