gamma Tubulin anticorps (Cy5.5)

N° du produit ABIN7091777

Détail du produit anti-gamma Tubulin anticorps (Cy5.5)

Antigène: gamma Tubulin (TUBG) (Tubulin, gamma (TUBG))

Reactivité: Souris, Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp gamma Tubulin est conjugé à/à la Cy5.5

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Western Blotting (WB)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein G.

Immunogène: KLH conjugated synthetic peptide derived from human Gamma Tubulin

Clone: 8D11

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Détails sur gamma Tubulin

Antigène: gamma Tubulin (TUBG) (Tubulin, gamma (TUBG))

Autre désignation: Gamma Tubulin (TUBG Produits)

Synonymes: anticorps Tubg2, anticorps xgam, anticorps tubulin gamma 1 L homeolog, anticorps tubg1.L

Sujet:

Synonyms: Centrosome Marker, Gamma 1 tubulin, gamma tubulin, gamma-tubulin, Gamma 2 tubulin, Gamma Tubulin 1, Gamma Tubulin 2, Gamma tubulin complex component 1, GCP 1, GCP-1, GCP1, MGC131994, TUBG, TUBG1, TUBG2, Tubulin gamma 1 chain, Tubulin gamma 2 chain, Xgam, TBG1_HUMAN, TBG2_HUMAN, Tubulin gamma-1 chain, Gamma-1-tubulin, Gamma-tubulin complex component 1.

Background: Centrosome Marker
Gamma tubulin, a member of the tubulin superfamily, is a ubiquitous and highly conserved protein within the microtubule organizing centre (MTOC). Gamma tubulin is not a component of microtubules, rather it functions as the microtubule nucleator at the MOTC, is responsible for binding microtubule minus ends and mediating the link between microtubles and the centrosome. By binding to the beta tubulin subunit of the tubulin molecule, it establishes the polarity of a microtubule leaving the alpha tubulin subunit exposed at the positive end.
The abundance of Gamma tubulin is less than 1 % of the level of either alpha or beta tubulin. It shares approximately 28-32 % identity with alpha tubulin from various organisms and 32-36 % identity with beta tubulins. The detection, localization and characterization of proteins involved in microtubule function is fundamental to the understanding of mitosis, meiosis and the microtubule cytoskeleton.

ID gène: 7283

UniProt: P23258