CD137 anticorps (AA 24-186)

N° du produit ABIN7092873

Cet anticorps Lapin Monoclonal détecte spécifiquement CD137 dans ELISA et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour CD137 anticorps (AA 24-186) (ABIN7092873)

Antigène: CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD137 est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Clone: DM66

Détail du produit anti-CD137 anticorps

Épitope: AA 24-186

Purification: Purified from cell culture supernatant by affinity chromatography

Immunogène: Recombinant human 4-1BB (Leu24-Gln186) (ABIN6961084) produced by using human HEK293 cells

Isotype: IgG

Information d'application

Indications d'application: ELISA 1/5000-10000,Flow Cyt  1/100

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.,0.1 % Procline 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détails sur CD137

Antigène: CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))

Autre désignation: 4-1BB

Sujet: Synonyms:TNFRSF9, 4-1BB, CD137, CDw137, ILA
Description:The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.

Poids moléculaire: 27.9kDa

ID gène: 3604

UniProt: Q07011

Pathways: Cancer Immune Checkpoints